In recognition of this 30th year of Learned Publishing, we dedicate our first issue of 2019 to questioning everything. Our goal is to examine the future of publishing through the window of evidence, rather than tradition and status quo. We invited diverse contributions who could bring fresh, honest thinking to some of our most widely held assumptions about scholarly and professional publishing. As special-issue editor, Andrew Plume, explains in his editorial, we aim to “Bring the facts, bust the myths.”